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Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence
BACKGROUND: Spindle assembly checkpoint components BubR1 and Sgo1 play a key role in the maintenance of chromosomal instability during cell division. These proteins function to block the anaphase entry until all condensed chromosomes have been attached by the microtubules emanating from both spindle...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743409/ https://www.ncbi.nlm.nih.gov/pubmed/26847209 http://dx.doi.org/10.1186/s13045-016-0238-5 |