Classification of P-glycoprotein-interacting compounds using machine learning methods

P-glycoprotein (Pgp) is a drug transporter that plays important roles in multidrug resistance and drug pharmacokinetics. The inhibition of Pgp has become a notable strategy for combating multidrug-resistant cancers and improving therapeutic outcomes. However, the polyspecific nature of Pgp, together...

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Detalles Bibliográficos
Autores principales: Prachayasittikul, Veda, Worachartcheewan, Apilak, Shoombuatong, Watshara, Prachayasittikul, Virapong, Nantasenamat, Chanin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743480/
https://www.ncbi.nlm.nih.gov/pubmed/26862321
http://dx.doi.org/10.17179/excli2015-374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743480/
https://www.ncbi.nlm.nih.gov/pubmed/26862321
http://dx.doi.org/10.17179/excli2015-374

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