MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

Motivation: Analysing the joint association between a large set of responses and predictors is a fundamental statistical task in integrative genomics, exemplified by numerous expression Quantitative Trait Loci (eQTL) studies. Of particular interest are the so-called ‘hotspots’, important genetic var...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewin, Alex, Saadi, Habib, Peters, James E., Moreno-Moral, Aida, Lee, James C., Smith, Kenneth G. C., Petretto, Enrico, Bottolo, Leonardo, Richardson, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743623/
https://www.ncbi.nlm.nih.gov/pubmed/26504141
http://dx.doi.org/10.1093/bioinformatics/btv568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743623/
https://www.ncbi.nlm.nih.gov/pubmed/26504141
http://dx.doi.org/10.1093/bioinformatics/btv568

Ejemplares similares