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Effect of MTHFR Gene Polymorphism Impact on Atherosclerosis via Genome-Wide Methylation

BACKGROUND: Atherosclerosis seriously threats human health. Homocysteine is an independent risk factor closely related to DNA methylation. MTHFR C667T loci polymorphism is closely associated with homocysteine level. This study aimed to investigate the relationship among MTHFR C667T loci polymorphism...

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Detalles Bibliográficos
Autores principales: Lin, Xuefeng, Zhang, Wei, Lu, Qun, Lei, Xinjun, Wang, Tingzhong, Han, Xuanmao, Ma, Aiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743680/
https://www.ncbi.nlm.nih.gov/pubmed/26828698
http://dx.doi.org/10.12659/MSM.895296