Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate

Non-syndromic (NS) cleft lip with or without cleft palate (CL/P) is a common disorder with a strong genetic underpinning. Genome-wide association studies have detected common variants associated with this disorder, but a large portion of the genetic risk for NSCL/P is conferred by unidentified rare...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Leslie, Elizabeth J., Jia, Zhonglin, Smith, Tiffany, Eshete, Mekonen, Butali, Azeez, Dunnwald, Martine, Murray, Jeffrey, Cornell, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743694/
https://www.ncbi.nlm.nih.gov/pubmed/26692521
http://dx.doi.org/10.1093/hmg/ddv614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743694/
https://www.ncbi.nlm.nih.gov/pubmed/26692521
http://dx.doi.org/10.1093/hmg/ddv614

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