The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells

Activated pancreatic stellate cells (PaSC) are key participants in the stroma of pancreatic cancer, secreting extracellular matrix proteins and inflammatory mediators. Tumors are poorly vascularized, creating metabolic stress conditions in cancer and stromal cells that necessitate adaptive homeostat...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Hsin-Yuan, Waldron, Richard T., Gong, Raymond, Ramanujan, V. Krishnan, Pandol, Stephen J., Lugea, Aurelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743835/
https://www.ncbi.nlm.nih.gov/pubmed/26849807
http://dx.doi.org/10.1371/journal.pone.0148999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743835/
https://www.ncbi.nlm.nih.gov/pubmed/26849807
http://dx.doi.org/10.1371/journal.pone.0148999

Ejemplares similares