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Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development

The lipid- and protein phosphatase PTEN is one of the most frequently mutated tumor suppressor genes in human cancers and many mutations found in tumor samples directly affect PTEN phosphatase activity. In order to understand the functional consequences of these mutations in vivo, the aim of our stu...

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Detalles Bibliográficos
Autores principales: Stumpf, Miriam, den Hertog, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743836/
https://www.ncbi.nlm.nih.gov/pubmed/26848951
http://dx.doi.org/10.1371/journal.pone.0148508