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Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development
The lipid- and protein phosphatase PTEN is one of the most frequently mutated tumor suppressor genes in human cancers and many mutations found in tumor samples directly affect PTEN phosphatase activity. In order to understand the functional consequences of these mutations in vivo, the aim of our stu...
Autores principales: | Stumpf, Miriam, den Hertog, Jeroen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743836/ https://www.ncbi.nlm.nih.gov/pubmed/26848951 http://dx.doi.org/10.1371/journal.pone.0148508 |
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