Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

A promising new drug target for the development of novel broad-spectrum antibiotics is the highly conserved small GTPase Obg (YhbZ, CgtA), a protein essential for the survival of all bacteria including Neisseria gonorrhoeae (GC). GC is the agent of gonorrhea, a prevalent sexually transmitted disease...

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Detalles Bibliográficos
Autores principales: Bonventre, Josephine A., Zielke, Ryszard A., Korotkov, Konstantin V., Sikora, Aleksandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743925/
https://www.ncbi.nlm.nih.gov/pubmed/26848972
http://dx.doi.org/10.1371/journal.pone.0148222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743925/
https://www.ncbi.nlm.nih.gov/pubmed/26848972
http://dx.doi.org/10.1371/journal.pone.0148222

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