Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis

Fhod3 is a cardiac member of the formin family proteins that play pivotal roles in actin filament assembly in various cellular contexts. The targeted deletion of mouse Fhod3 gene leads to defects in cardiogenesis, particularly during myofibrillogenesis, followed by lethality at embryonic day (E) 11....

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Detalles Bibliográficos
Autores principales: Fujimoto, Noriko, Kan-o, Meikun, Ushijima, Tomoki, Kage, Yohko, Tominaga, Ryuji, Sumimoto, Hideki, Takeya, Ryu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744011/
https://www.ncbi.nlm.nih.gov/pubmed/26848968
http://dx.doi.org/10.1371/journal.pone.0148472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744011/
https://www.ncbi.nlm.nih.gov/pubmed/26848968
http://dx.doi.org/10.1371/journal.pone.0148472

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