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In Vivo, In Vitro, and In Silico Characterization of Peptoids as Antimicrobial Agents

Bacterial resistance to conventional antibiotics is a global threat that has spurred the development of antimicrobial peptides (AMPs) and their mimetics as novel anti-infective agents. While the bioavailability of AMPs is often reduced due to protease activity, the non-natural structure of AMP mimet...

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Detalles Bibliográficos
Autores principales: Czyzewski, Ann M., Jenssen, Håvard, Fjell, Christopher D., Waldbrook, Matt, Chongsiriwatana, Nathaniel P., Yuen, Eddie, Hancock, Robert E. W., Barron, Annelise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744035/
https://www.ncbi.nlm.nih.gov/pubmed/26849681
http://dx.doi.org/10.1371/journal.pone.0135961