Cargando…
Structures of the EphA2 Receptor at the Membrane: Role of Lipid Interactions
Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal ectodomain binds ligands and enables receptor clustering, which activates the intracellular kinase. Relatively little is known about the function of the membrane-proximal fibronectin domain 2 (FN2) of the ectodomain. M...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744086/ https://www.ncbi.nlm.nih.gov/pubmed/26724997 http://dx.doi.org/10.1016/j.str.2015.11.008 |