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The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells

Despite the risk of transmitting HIV-1, mothers in resource-poor areas are encouraged to breastfeed their infants due to beneficial immunologic and nutritional factors in milk. Interestingly, in the absence of antiretroviral prophylaxis, the overwhelming majority of HIV-1-exposed, breastfeeding infa...

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Detalles Bibliográficos
Autores principales: Jeffries, Thomas L, Sacha, CR, Pollara, Justin, Himes, Jon, Jaeger, Frederick H, Dennison, S Moses, McGuire, Erin, Kunz, Erika, Eudailey, Joshua A, Trama, Ashley M, LaBranche, Celia, Fouda, Genevieve G, Wiehe, Kevin, Montefiori, David C, Haynes, Barton F, Liao, Hua-Xin, Ferrari, Guido, Alam, S Munir, Moody, M Anthony, Permar, Sallie R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744153/
https://www.ncbi.nlm.nih.gov/pubmed/26242599
http://dx.doi.org/10.1038/mi.2015.70