Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma

Aberrant expression of cancer genes and non-canonical RNA species is a hallmark of cancer. However, the mechanisms driving such atypical gene expression programs are incompletely understood. Here, our transcriptional profiling of a cohort of 50 primary clear cell renal cell carcinoma (ccRCC) samples...

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Detalles Bibliográficos
Autores principales: Grosso, Ana R, Leite, Ana P, Carvalho, Sílvia, Matos, Mafalda R, Martins, Filipa B, Vítor, Alexandra C, Desterro, Joana MP, Carmo-Fonseca, Maria, de Almeida, Sérgio F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744188/
https://www.ncbi.nlm.nih.gov/pubmed/26575290
http://dx.doi.org/10.7554/eLife.09214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744188/
https://www.ncbi.nlm.nih.gov/pubmed/26575290
http://dx.doi.org/10.7554/eLife.09214

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