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Controlling the response to DNA damage by the APC/C-Cdh1

Proper cell cycle progression is safeguarded by the oscillating activities of cyclin/cyclin-dependent kinase complexes. An important player in the regulation of mitotic cyclins is the anaphase-promoting complex/cyclosome (APC/C), a multi-subunit E3 ubiquitin ligase. Prior to entry into mitosis, the...

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Detalles Bibliográficos
Autores principales: de Boer, H. Rudolf, Guerrero Llobet, S., van Vugt, Marcel A. T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744251/
https://www.ncbi.nlm.nih.gov/pubmed/26650195
http://dx.doi.org/10.1007/s00018-015-2096-7