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A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo

BACKGROUND: The ability of Zn(II) and Cu(II) metal complexes of non-steroidal anti-inflammatory drugs (NSAIDs) to inhibit acute arterial inflammation in vivo has been studied. RESULTS: When acute vascular inflammation was induced in normocholesterolemic New Zealand White rabbits by inserting a non-o...

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Detalles Bibliográficos
Autores principales: Puranik, Rajesh, Bao, Shisan, Bonin, Antonio M., Kaur, Ravinder, Weder, Jane E., Casbolt, Llewellyn, Hambley, Trevor W., Lay, Peter A., Barter, Philip J., Rye, Kerry-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744413/
https://www.ncbi.nlm.nih.gov/pubmed/26855766
http://dx.doi.org/10.1186/s13578-016-0076-8