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Multiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivo

BACKGROUND: The axonal tau protein is a tubulin-binding protein, which plays important roles in the formation and stability of the microtubule. Mutations in the tau gene are associated with familial forms of frontotemporal dementia with Parkinsonism linked to chromosome-17 (FTDP-17). Paired helical...

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Detalles Bibliográficos
Autores principales: Wu, Bo-Kai, Yuan, Rey-Yue, Lien, Huang-Wei, Hung, Chin-Chun, Hwang, Pung-Pung, Chen, Rita Pei-Yeh, Chang, Chun-Che, Liao, Yung-Feng, Huang, Chang-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744436/
https://www.ncbi.nlm.nih.gov/pubmed/26852117
http://dx.doi.org/10.1186/s12929-016-0237-4