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Multiple signaling factors and drugs alleviate neuronal death induced by expression of human and zebrafish tau proteins in vivo
BACKGROUND: The axonal tau protein is a tubulin-binding protein, which plays important roles in the formation and stability of the microtubule. Mutations in the tau gene are associated with familial forms of frontotemporal dementia with Parkinsonism linked to chromosome-17 (FTDP-17). Paired helical...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744436/ https://www.ncbi.nlm.nih.gov/pubmed/26852117 http://dx.doi.org/10.1186/s12929-016-0237-4 |