d‐amino acid oxidase knockout (Dao (−/−)) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption

d‐amino acid oxidase (DAO, DAAO) is an enzyme that degrades d‐serine, the primary endogenous co‐agonist of the synaptic N‐methyl‐d‐aspartate receptor. Convergent evidence implicates DAO in the pathophysiology and potential treatment of schizophrenia. To better understand the functional role of DAO,...

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Detalles Bibliográficos
Autores principales: Pritchett, David, Hasan, Sibah, Tam, Shu K. E., Engle, Sandra J., Brandon, Nicholas J., Sharp, Trevor, Foster, Russell G., Harrison, Paul J., Bannerman, David M., Peirson, Stuart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744680/
https://www.ncbi.nlm.nih.gov/pubmed/25816902
http://dx.doi.org/10.1111/ejn.12880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744680/
https://www.ncbi.nlm.nih.gov/pubmed/25816902
http://dx.doi.org/10.1111/ejn.12880

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