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Intrinsic properties of germinal center‐derived B cells promote their enhanced class switching to IgE

BACKGROUND: Research on the origins and development of human IgE‐expressing (IgE(+)) cells is required for understanding the pathogenesis of allergy and asthma. These studies have been thwarted by the rarity of IgE(+) cells in vivo and the low frequency of class switch recombination (CSR) to IgE ex ...

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Detalles Bibliográficos
Autores principales: Ramadani, F., Upton, N., Hobson, P., Chan, Y.‐C., Mzinza, D., Bowen, H., Kerridge, C., Sutton, B. J., Fear, D. J., Gould, H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744720/
https://www.ncbi.nlm.nih.gov/pubmed/26109279
http://dx.doi.org/10.1111/all.12679