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Microenvironmental control of stem cell fate in intestinal homeostasis and disease

The conventional model of intestinal epithelial architecture describes a unidirectional tissue organizational hierarchy with stem cells situated at the crypt base and daughter cells proliferating and terminally differentiating as they progress along the vertical (crypt–luminal) axis. In this model,...

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Detalles Bibliográficos
Autores principales: Biswas, Sujata, Davis, Hayley, Irshad, Shazia, Sandberg, Tessa, Worthley, Daniel, Leedham, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744721/
https://www.ncbi.nlm.nih.gov/pubmed/25974319
http://dx.doi.org/10.1002/path.4563