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The exploration of network motifs as potential drug targets from post-translational regulatory networks

Phosphorylation and proteolysis are among the most common post-translational modifications (PTMs), and play critical roles in various biological processes. More recent discoveries imply that the crosstalks between these two PTMs are involved in many diseases. In this work, we construct a post-transl...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Dong, Song, Jiangning, Bork, Peer, Zhao, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744934/
https://www.ncbi.nlm.nih.gov/pubmed/26853265
http://dx.doi.org/10.1038/srep20558