Prostaglandins E2 signal mediated by receptor subtype EP2 promotes IgE production in vivo and contributes to asthma development

Prostaglandins E2 (PGE2) has been shown to enhance IgE production by B cells in vitro. The physiological and pathological relevance of this phenomenon and the underlying molecular mechanism, however, remain to be elucidated. B cells from wild type and EP2-deficient mice were compared in culture for...

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Detalles Bibliográficos
Autores principales: Gao, Yuhan, Zhao, Chunyan, Wang, Wei, Jin, Rong, Li, Qian, Ge, Qing, Guan, Youfei, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744937/
https://www.ncbi.nlm.nih.gov/pubmed/26852804
http://dx.doi.org/10.1038/srep20505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744937/
https://www.ncbi.nlm.nih.gov/pubmed/26852804
http://dx.doi.org/10.1038/srep20505

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