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Prostaglandins E2 signal mediated by receptor subtype EP2 promotes IgE production in vivo and contributes to asthma development
Prostaglandins E2 (PGE2) has been shown to enhance IgE production by B cells in vitro. The physiological and pathological relevance of this phenomenon and the underlying molecular mechanism, however, remain to be elucidated. B cells from wild type and EP2-deficient mice were compared in culture for...
Autores principales: | Gao, Yuhan, Zhao, Chunyan, Wang, Wei, Jin, Rong, Li, Qian, Ge, Qing, Guan, Youfei, Zhang, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744937/ https://www.ncbi.nlm.nih.gov/pubmed/26852804 http://dx.doi.org/10.1038/srep20505 |
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