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A perfusion bioreactor system efficiently generates cell‐loaded bone substitute materials for addressing critical size bone defects

Critical size bone defects and non‐union fractions are still challenging to treat. Cell‐loaded bone substitutes have shown improved bone ingrowth and bone formation. However, a lack of methods for homogenously colonizing scaffolds limits the maximum volume of bone grafts. Additionally, therapy robus...

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Detalles Bibliográficos
Autores principales: Kleinhans, Claudia, Mohan, Ramkumar Ramani, Vacun, Gabriele, Schwarz, Thomas, Haller, Barbara, Sun, Yang, Kahlig, Alexander, Kluger, Petra, Finne‐Wistrand, Anna, Walles, Heike, Hansmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744951/
https://www.ncbi.nlm.nih.gov/pubmed/26011163
http://dx.doi.org/10.1002/biot.201400813