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A perfusion bioreactor system efficiently generates cell‐loaded bone substitute materials for addressing critical size bone defects
Critical size bone defects and non‐union fractions are still challenging to treat. Cell‐loaded bone substitutes have shown improved bone ingrowth and bone formation. However, a lack of methods for homogenously colonizing scaffolds limits the maximum volume of bone grafts. Additionally, therapy robus...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY‐VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744951/ https://www.ncbi.nlm.nih.gov/pubmed/26011163 http://dx.doi.org/10.1002/biot.201400813 |