Flexible selection of a single treatment incorporating short‐term endpoint information in a phase II/III clinical trial

Seamless phase II/III clinical trials in which an experimental treatment is selected at an interim analysis have been the focus of much recent research interest. Many of the methods proposed are based on the group sequential approach. This paper considers designs of this type in which the treatment...

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Detalles Bibliográficos
Autores principales: Stallard, Nigel, Kunz, Cornelia Ursula, Todd, Susan, Parsons, Nicholas, Friede, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745001/
https://www.ncbi.nlm.nih.gov/pubmed/26112909
http://dx.doi.org/10.1002/sim.6567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745001/
https://www.ncbi.nlm.nih.gov/pubmed/26112909
http://dx.doi.org/10.1002/sim.6567

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