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Flexible selection of a single treatment incorporating short‐term endpoint information in a phase II/III clinical trial
Seamless phase II/III clinical trials in which an experimental treatment is selected at an interim analysis have been the focus of much recent research interest. Many of the methods proposed are based on the group sequential approach. This paper considers designs of this type in which the treatment...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745001/ https://www.ncbi.nlm.nih.gov/pubmed/26112909 http://dx.doi.org/10.1002/sim.6567 |