An Engineered Rare Codon Device for Optimization of Metabolic Pathways

Rare codons generally arrest translation due to rarity of their cognate tRNAs. This property of rare codons can be utilized to regulate protein expression. In this study, a linear relationship was found between expression levels of genes and copy numbers of rare codons inserted within them. Based on...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, You, Li, Chunying, Khan, Md. Rezaul Islam, Wang, Yushu, Ruan, Yunfeng, Zhao, Bin, Zhang, Bo, Ma, Xiaopan, Zhang, Kaisi, Zhao, Xiwen, Ye, Guanhao, Guo, Xizhi, Feng, Guoyin, He, Lin, Ma, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745014/
https://www.ncbi.nlm.nih.gov/pubmed/26852704
http://dx.doi.org/10.1038/srep20608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745014/
https://www.ncbi.nlm.nih.gov/pubmed/26852704
http://dx.doi.org/10.1038/srep20608

Ejemplares similares