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Single‐residue posttranslational modification sites at the N‐terminus, C‐terminus or in‐between: To be or not to be exposed for enzyme access

Many protein posttranslational modifications (PTMs) are the result of an enzymatic reaction. The modifying enzyme has to recognize the substrate protein's sequence motif containing the residue(s) to be modified; thus, the enzyme's catalytic cleft engulfs these residue(s) and the respective...

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Detalles Bibliográficos
Autores principales: Sirota, Fernanda L., Maurer‐Stroh, Sebastian, Eisenhaber, Birgit, Eisenhaber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745020/
https://www.ncbi.nlm.nih.gov/pubmed/26038108
http://dx.doi.org/10.1002/pmic.201400633