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Tuned by metals: the TET peptidase activity is controlled by 3 metal binding sites

TET aminopeptidases are dodecameric particles shared in the three life domains involved in various biological processes, from carbon source provider in archaea to eye-pressure regulation in humans. Each subunit contains a dinuclear metal site (M1 and M2) responsible for the enzyme catalytic activity...

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Detalles Bibliográficos
Autores principales: Colombo, Matteo, Girard, Eric, Franzetti, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745047/
https://www.ncbi.nlm.nih.gov/pubmed/26853450
http://dx.doi.org/10.1038/srep20876