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Tuned by metals: the TET peptidase activity is controlled by 3 metal binding sites
TET aminopeptidases are dodecameric particles shared in the three life domains involved in various biological processes, from carbon source provider in archaea to eye-pressure regulation in humans. Each subunit contains a dinuclear metal site (M1 and M2) responsible for the enzyme catalytic activity...
Autores principales: | Colombo, Matteo, Girard, Eric, Franzetti, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745047/ https://www.ncbi.nlm.nih.gov/pubmed/26853450 http://dx.doi.org/10.1038/srep20876 |
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