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Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier

Physiologic barriers such as the blood placenta barrier (BPB) and the blood brain barrier protect the underlying parenchyma from pathogens and toxins. ATP-binding cassette (ABC) transporters are transmembrane proteins found at these barriers, and function to efflux xenobiotics and maintain chemical...

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Detalles Bibliográficos
Autores principales: Kumar, Jeyan S., Wei, Bih-Rong, Madigan, James P., Simpson, R. Mark, Hall, Matthew D., Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745077/
https://www.ncbi.nlm.nih.gov/pubmed/26853103
http://dx.doi.org/10.1038/srep20418