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Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier
Physiologic barriers such as the blood placenta barrier (BPB) and the blood brain barrier protect the underlying parenchyma from pathogens and toxins. ATP-binding cassette (ABC) transporters are transmembrane proteins found at these barriers, and function to efflux xenobiotics and maintain chemical...
Autores principales: | Kumar, Jeyan S., Wei, Bih-Rong, Madigan, James P., Simpson, R. Mark, Hall, Matthew D., Gottesman, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745077/ https://www.ncbi.nlm.nih.gov/pubmed/26853103 http://dx.doi.org/10.1038/srep20418 |
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