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Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis

BACKGROUND: Increasing resistance to anti-tuberculosis drugs has driven the need for developing new drugs. Resources such as the tropical disease research (TDR) target database and AssessDrugTarget can help to prioritize putative drug targets. Hower, these resources do not necessarily map to metabol...

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Detalles Bibliográficos
Autores principales: Cloete, Ruben, Oppon, Ekow, Murungi, Edwin, Schubert, Wolf-Dieter, Christoffels, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745158/
https://www.ncbi.nlm.nih.gov/pubmed/26856535
http://dx.doi.org/10.1186/s12859-016-0898-8