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Downregulation of the Yes-Associated Protein Is Associated with Extracellular Matrix Disorders in Ascending Aortic Aneurysms

Previous studies indicate that extracellular matrix (ECM) disorders lead to the apoptosis of Vascular Smooth Muscle Cells (VSMCs), which impairs the aortic wall by reducing the generation of elastic fibers, and ultimately result in ascending aortic aneurysm. The critical role of the Yes-associated p...

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Detalles Bibliográficos
Autores principales: Li, Haiyang, Jiang, Wenjian, Ren, Weihong, Guo, Dong, Guo, Jialong, Wang, Xiaolong, Liu, Yuyong, Lan, Feng, Du, Jie, Zhang, Hongjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745276/
https://www.ncbi.nlm.nih.gov/pubmed/26904131
http://dx.doi.org/10.1155/2016/6786184