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Osteoclasts Are Required for Hematopoietic Stem and Progenitor Cell Mobilization but Not for Stress Erythropoiesis in Plasmodium chabaudi adami Murine Malaria

The anemia and inflammation concurrent with blood stage malaria trigger stress haematopoiesis and erythropoiesis. The activity of osteoclasts seems required for the mobilization of hematopoietic stem and progenitor cells (HSPC) from the bone marrow to the periphery. Knowing that BALB/c mice with acu...

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Detalles Bibliográficos
Autores principales: Roméro, Hugo, Warburton, Christopher, Sanchez-Dardon, Jaime, Scorza, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745282/
https://www.ncbi.nlm.nih.gov/pubmed/26903708
http://dx.doi.org/10.1155/2016/3909614