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Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Nephrotoxicity is one of the limiting factors for using doxorubicin (DOX). Interleukin 1 has major role in DOX-induced nephrotoxicity, so we investigated the effect of interleukin 1 receptor antagonist diacerein (DIA) on DOX-induced nephrotoxicity. DIA (25 and 50 mg/kg/day) was administered orally t...

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Detalles Bibliográficos
Autores principales: Refaie, Marwa M. M., Amin, Entesar F., El-Tahawy, Nashwa F., Abdelrahman, Aly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745331/
https://www.ncbi.nlm.nih.gov/pubmed/26904117
http://dx.doi.org/10.1155/2016/9507563