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Risperidone-associated adverse drug reactions and CYP2D6 polymorphisms in a South African cohort

BACKGROUND: Contradictory information exists regarding the influence of CYP2D6 polymorphisms on adverse drug reactions (ADRs) (extrapyramidal symptoms (EPS) and weight gain) related to risperidone treatment. This prompted us to evaluate the influence of CYP2D6 genetic variation in a cohort of South...

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Detalles Bibliográficos
Autores principales: Dodgen, Tyren M., Eloff, Arinda, Mataboge, Connie, Roos, Louw (.J.L.)., van Staden, Werdie (.C.W.)., Pepper, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745369/
https://www.ncbi.nlm.nih.gov/pubmed/26937359
http://dx.doi.org/10.1016/j.atg.2015.05.001