Inhibition of 13-cis retinoic acid-induced gene expression of reactive-resistance genes by thalidomide in glioblastoma tumours in vivo

The cell differentiation potential of 13-cis retinoic acid (RA) has not succeeded in the clinical treatment of glioblastoma (GBM) so far. However, RA may also induce the expression of resistance genes such as HOXB7 which can be suppressed by Thalidomide (THAL). Therefore, we tested if combined treat...

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Detalles Bibliográficos
Autores principales: Milanovic, Dusan, Sticht, Carsten, Röhrich, Manuel, Maier, Patrick, Grosu, Anca-L., Herskind, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745702/
https://www.ncbi.nlm.nih.gov/pubmed/26362268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745702/
https://www.ncbi.nlm.nih.gov/pubmed/26362268

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