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Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis

Despite being an attractive molecular target for both lymphoid and myeloid leukemias characterized by activated tyrosine kinases, the molecular and physiological consequences of reduced signal transducer and activator of transcription-5 (Stat5) during leukemogenesis are not well known. Stat5 is a cr...

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Detalles Bibliográficos
Autores principales: Wang, Zhengqi, Medrzycki, Magdalena, Bunting, Silvia T., Bunting, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745704/
https://www.ncbi.nlm.nih.gov/pubmed/26338970