Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy

While several new therapies are FDA-approved for bone-metastatic prostate cancer (PCa), patient survival has only improved marginally. Here, we report that chitosan nanoparticle-mediated delivery of miR-34a, a tumor suppressive microRNA that downregulates multiple gene products involved in PCa progr...

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Detalles Bibliográficos
Autores principales: Gaur, Sanchaika, Wen, Yunfei, Song, Jian H., Parikh, Nila U., Mangala, Lingegowda S., Blessing, Alicia M., Ivan, Cristina, Wu, Sherry Y., Varkaris, Andreas, Shi, Yan, Lopez-Berestein, Gabriel, Frigo, Daniel E., Sood, Anil K., Gallick, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745718/
https://www.ncbi.nlm.nih.gov/pubmed/26313360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745718/
https://www.ncbi.nlm.nih.gov/pubmed/26313360

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