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Exposure to airborne PM(2.5) suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells

Long-term exposure to airborne PM(2.5) is associated with increased lung cancer risk but the underlying mechanism remains unclear. We characterized global microRNA and mRNA expression in human bronchial epithelial cells exposed to PM(2.5) organic extract and integrally analyzed microRNA-mRNA interac...

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Detalles Bibliográficos
Autores principales: Liu, Chunling, Guo, Huan, Cheng, Xinxin, Shao, Mingming, Wu, Chen, Wang, Suhan, Li, Hongmin, Wei, Lixuan, Gao, Yanning, Tan, Wen, Cheng, Shujun, Wu, Tangchun, Yu, Dianke, Lin, Dongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745737/
https://www.ncbi.nlm.nih.gov/pubmed/26338969