Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study

Gliomas are the most common primary brain tumors. To date, therapies do not allow curing patients, and glioblastomas (GBMs) are associated with remarkably poor prognosis. This situation is at least partly due to intrinsic or acquired resistance to treatment, especially to chemotherapy. In 2005, temo...

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Detalles Bibliográficos
Autores principales: Boccard, Sandra G., Marand, Sandie V., Geraci, Sandra, Pycroft, Laurie, Berger, François R., Pelletier, Laurent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745739/
https://www.ncbi.nlm.nih.gov/pubmed/26336131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745739/
https://www.ncbi.nlm.nih.gov/pubmed/26336131

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