Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activation

Angiogenesis plays a critical role in the growth and metastasis of tumors, which makes it an attractive target for anti-tumor drug development. Deoxypodophyllotoxin (DPT), a natural product isolated from Anthriscus sylvestris, inhibits cell proliferation and migration in various cancer cell types. O...

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Detalles Bibliográficos
Autores principales: Wang, Yurong, Wang, Bin, Guerram, Mounia, Sun, Li, Shi, Wei, Tian, Chongchong, Zhu, Xiong, Jiang, Zhenzhou, Zhang, Luyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745742/
https://www.ncbi.nlm.nih.gov/pubmed/26470595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745742/
https://www.ncbi.nlm.nih.gov/pubmed/26470595

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