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Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model

Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer. However, especially after incomplete cytoreduction, disease progression is common and this is likely due to limited ti...

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Detalles Bibliográficos
Autores principales: Gremonprez, Félix, Descamps, Benedicte, Izmer, Andrei, Vanhove, Christian, Vanhaecke, Frank, De Wever, Olivier, Ceelen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745770/
https://www.ncbi.nlm.nih.gov/pubmed/26375674