Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

Elucidating the targets and mechanism of action of natural products is strategically important prior to drug development and assessment of potential clinical applications. In this report, we elucidated the main targets and mechanism of action of the natural product tonantzitlolone (TZL) in clear cel...

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Detalles Bibliográficos
Autores principales: Sourbier, Carole, Scroggins, Bradley T., Mannes, Philip Z., Liao, Pei-Jyun, Siems, Karsten, Wolf, Dietmar, Beutler, John A., Linehan, W. Marston, Neckers, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745775/
https://www.ncbi.nlm.nih.gov/pubmed/26298773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745775/
https://www.ncbi.nlm.nih.gov/pubmed/26298773

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