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Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution

Intrinsic apoptosis eliminates cells with damaged DNA and cells with dysregulated expression of oncogene. PGAM5, a member of the phosphoglycerate mutase family, has two splicing variants: PGAM5L (the long form) and PGAM5S (the short form). It has been well established that PGAM5 is at the convergent...

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Detalles Bibliográficos
Autores principales: Xu, Wenjuan, Jing, Linlin, Wang, Quanshi, Lin, Chung-Chih, Chen, Xiaoting, Diao, Jianxin, Liu, Yuanliang, Sun, Xuegang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745779/
https://www.ncbi.nlm.nih.gov/pubmed/26356820