Cargando…
Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution
Intrinsic apoptosis eliminates cells with damaged DNA and cells with dysregulated expression of oncogene. PGAM5, a member of the phosphoglycerate mutase family, has two splicing variants: PGAM5L (the long form) and PGAM5S (the short form). It has been well established that PGAM5 is at the convergent...
Autores principales: | Xu, Wenjuan, Jing, Linlin, Wang, Quanshi, Lin, Chung-Chih, Chen, Xiaoting, Diao, Jianxin, Liu, Yuanliang, Sun, Xuegang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745779/ https://www.ncbi.nlm.nih.gov/pubmed/26356820 |
Ejemplares similares
-
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation
por: Han, Qinrui, et al.
Publicado: (2021) -
Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
por: Wang, Ping, et al.
Publicado: (2015) -
DRP1 interacts directly with BAX to induce its activation and apoptosis
por: Jenner, Andreas, et al.
Publicado: (2022) -
Mitochondrial PGAM5−Drp1 signaling regulates the metabolic reprogramming of macrophages and regulates the induction of inflammatory responses
por: Bang, Bo-Ram, et al.
Publicado: (2023) -
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling
por: Kang, Young Jun, et al.
Publicado: (2015)