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Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer

Histone deacetylase 6 (HDAC6) is a unique member of the histone deacetylase family. Although HDAC6 is mainly localized in the cytoplasm, it can regulate the activities of the transcription factors in the nucleus. However, a correlation of intracellular distribution of HDAC6 with tumor progression is...

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Detalles Bibliográficos
Autores principales: Yang, Chih-Jen, Liu, Yu-Peng, Dai, Hong-Ying, Shiue, Yow-Ling, Tsai, Chia-Jung, Huang, Ming-Shyan, Yeh, Yao-Tsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745796/
https://www.ncbi.nlm.nih.gov/pubmed/26388610