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Mechanistic analysis of Zein nanoparticles/PLGA triblock in situ forming implants for glimepiride
OBJECTIVES: The study aims at applying pharmaceutical nanotechnology and D-optimal fractional factorial design to screen and optimize the high-risk variables affecting the performance of a complex drug delivery system consisting of glimepiride–Zein nanoparticles and inclusion of the optimized formul...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745829/ https://www.ncbi.nlm.nih.gov/pubmed/26893561 http://dx.doi.org/10.2147/IJN.S99731 |